Study Detail

TitleNovel AID target loci sharing unique features with immunoglobulin genes
Study TypeWhole Genome Sequencing
Abstract Activation-induced cytidine deaminase (AID) is required for both somatic hypermutation (SHM) and class switch recombination (CSR) in activated B cells. It is also known that AID targets non-immunoglobulin genes, and introduces mutations or chromosomal translocations, eventually causing tumors. In or .. [more]
Description none provided
Center NameRIKEN_OSC