Study Detail

TitleSall1 co-operates with Six2 to actively maintain nephron progenitors
Study TypeEpigenetics
Abstract The balanced self-renewal and differentiation of nephron progenitors is critical for kidney development. While a nuclear factor Sall1 is essential for kidney formation, its role in the nephron progenitors remains unknown. We here report that Sall1 deletion in the Six2-positive nephron progenitors an .. [more]