Study Detail

TitleHistone H4 Lys 20 mono-methylation of the CENP-A nucleosome is essential for kinetochore assembly
Study TypeEpigenetics
Abstract In vertebrate cells, centromeres are specified epigenetically through the deposition of the centromere-specific histone CENP-A. Following CENP-A deposition, additional proteins are assembled on centromeric chromatin. Although deposition of CENP-A is critical for centromere specification, it remains .. [more]
Center NameNIG