Study Detail

TitleEzh2 restricts activation of fetal gene signature in adult hematopoietic stem and progenitor cells
Study TypeOther
Abstract Fetal liver hematopoietic stem cells seed bone marrow (BM) and undergo reprograming into adult type that are largely quiescent and restricted in their self-renewal activity. Here we show that in the absence of the polycomb-group gene Ezh2, a cohort of fetal-specific genes, including let-7 target gen .. [more]
Description Fetal liver hematopoietic stem cells seed bone marrow (BM) and undergo reprograming into adult type that are largely quiescent and restricted in their self-renewal activity. Here we show that in the absence of the polycomb-group gene Ezh2, a cohort of fetal-specific genes, including let-7 target gen .. [more]
Center NameCHIBA_U