Study Detail

TitleEzh2 loss in hematopoietic stem cells predisposes mice to develop heterogeneous malignancies in an Ezh1-depenedent manner
Study TypeOther
Abstract Recent genome sequencing revealed inactivating mutations in EZH2, which encodes an enzymatic component of polycomb repressive complex 2 (PRC2), in patients with myelodysplastic syndrome (MDS), myeloproliferative neoplasms (MPN) and MDS/MPN overlap disorders. We herein demonstrated that the hematopoi .. [more]
Description Recent genome sequencing revealed inactivating mutations in EZH2, which encodes an enzymatic component of polycomb repressive complex 2 (PRC2), in patients with myelodysplastic syndrome (MDS), myeloproliferative neoplasms (MPN) and MDS/MPN overlap disorders. We herein demonstrated that the hematopoi .. [more]
Center NameCHIBA_U