Study Detail

TitleImpacts of combinatorial dysfunction of epigenetic regulators Tet2 and Ezh2 on epigenome in the pathogenesis of myelodysplastic syndrome
Study TypeOther
Abstract Somatic inactivating mutations of epigenetic regulators are frequently found in combination in myelodysplastic syndrome (MDS). However, it remains unknown how combinatory mutations in epigenetic regulators promote development of MDS. Here, we performed epigenomic profilings of hematopoietic stem and .. [more]
Description Somatic inactivating mutations of epigenetic regulators are frequently found in combination in myelodysplastic syndrome (MDS). However, it remains unknown how combinatory mutations in epigenetic regulators promote development of MDS. Here, we performed epigenomic profilings of hematopoietic stem and .. [more]
Center NameCHIBA_U