Study Detail

TitleEpigenetic regulation of hematopoietic stem and progenitor cells by the Eset histone methyltranferase.
Study TypeOther
Abstract Methylation of histone H3 at lysine 9 (H3K9) mediates heterochromatin formation by forming a binding site for HP1. ERG-associated protein with a SET domain (Eset) or Setdb1E is a methyltransferase which trimethylates H3K9 in the euchromatic region. In mice, homozygous mutations of Eset result in per .. [more]
Description Methylation of histone H3 at lysine 9 (H3K9) mediates heterochromatin formation by forming a binding site for HP1. ERG-associated protein with a SET domain (Eset) or Setdb1E is a methyltransferase which trimethylates H3K9 in the euchromatic region. In mice, homozygous mutations of Eset result in per .. [more]
Center NameHIROSHIMA