Study Detail

TitleFam60a is a component of the mSin3A-HDAC transcriptional corepressor complex and inhibits Tet-mediated DNA demethylation
Study TypeOther
Abstract Fam60a was identified as a highly expressed gene of unknown function in mouse embryonic stem cells. We have examined the role of Fam60a in mouse development. Most Fam60a mutant embryos manifest hypoplasia of visceral organs and die in utero. Fam60a interacts with components of the mSin3A-HDAC transc .. [more]
Description Fam60a was identified as a highly expressed gene of unknown function in mouse embryonic stem cells. We have examined the role of Fam60a in mouse development. Most Fam60a mutant embryos manifest hypoplasia of visceral organs and die in utero. Fam60a interacts with components of the mSin3A-HDAC transc .. [more]
Center NameRIKEN_CDB