Study Detail

TitleLATS2 knockout causes PRC2 dysregulation and global H3K27me3 loss in HeLa-S3
Study TypeOther
Abstract We report that knockout of LATS2 gene caused up-regulation of genes which are repressed by PRC2 partially independent of canonical hippo-YAP/TAZ signaling cascade in HeLa-S3 using both microarray and RNA-sequencing. LATS2 KO dependent down-regulation of PRC2 caused global H3K27me3 reduction and dysr .. [more]
Description We report that knockout of LATS2 gene caused up-regulation of genes which are repressed by PRC2 partially independent of canonical hippo-YAP/TAZ signaling cascade in HeLa-S3 using both microarray and RNA-sequencing. LATS2 KO dependent down-regulation of PRC2 caused global H3K27me3 reduction and dysr .. [more]
Center NameKUFMS