Study Detail

TitleBcor insufficiency promotes initiation and progression of myelodysplastic syndrome
Study TypeOther
Abstract BCOR, encoding BCL-6 co-repressor (BCOR), is X-linked and targeted by somatic mutations in various hematological malignancies including myelodysplastic syndrome (MDS). We previously reported that mice lacking Bcor exon 4 (Bcor dE4/y) in the hematopoietic compartment developed NOTCH-dependent acute T .. [more]
Description BCOR, encoding BCL-6 co-repressor (BCOR), is X-linked and targeted by somatic mutations in various hematological malignancies including myelodysplastic syndrome (MDS). We previously reported that mice lacking Bcor exon 4 (Bcor dE4/y) in the hematopoietic compartment developed NOTCH-dependent acute T .. [more]
Center NameCHIBA_U