Study Detail

TitleGene expression profiles in control and Setdb1-KD PGCLCs
Study TypeOther
Abstract In mice, primordial germ cells (PGCs), which are the precursors of gametes, are fate-determined from pluripotent epiblasts. The epigenetic regulation of PGC fate determination remains poorly understood. We identify histone methyltransferase Setdb1 as an epigenetic regulator of PGC fate determination .. [more]
Description In mice, primordial germ cells (PGCs), which are the precursors of gametes, are fate-determined from pluripotent epiblasts. The epigenetic regulation of PGC fate determination remains poorly understood. We identify histone methyltransferase Setdb1 as an epigenetic regulator of PGC fate determination .. [more]
Center NameTUAGRI