Study Detail

TitleBmi1 counteracts hematopoietic stem cell aging by suppressing ectopic activation of bivalent domains and developmental genes
Study TypeOther
Abstract Polycomb-group (PcG) proteins are essential for stem cell regulation. We previously demonstrated Bmi1, a component of PcG complexes, could enhance the regenerative capacity of hematopoietic stem cells (HSCs). Here we challenged to encounter age-related loss of stem cell functions by persistent expre .. [more]
Description Polycomb-group (PcG) proteins are essential for stem cell regulation. We previously demonstrated Bmi1, a component of PcG complexes, could enhance the regenerative capacity of hematopoietic stem cells (HSCs). Here we challenged to encounter age-related loss of stem cell functions by persistent expre .. [more]
Center NameCHIBA_U