Study Detail

TitleThe chromatin binding protein Phf6 restricts the self-renewal of hematopoietic stem cells
Study TypeOther
Abstract Recurrent inactivating mutations have been identified in the X-linked PHF6 gene, encoding a chromatin-binding transcriptional regulator protein, in various hematological malignancies. However, the role of PHF6 in normal hematopoiesis and its tumor suppressor function remain largely unknown. We herei .. [more]
Description Recurrent inactivating mutations have been identified in the X-linked PHF6 gene, encoding a chromatin-binding transcriptional regulator protein, in various hematological malignancies. However, the role of PHF6 in normal hematopoiesis and its tumor suppressor function remain largely unknown. We herei .. [more]
Center NameCHIBA_U