Study Detail

TitleProtease capable of degrading osteoprotegerin in the bone microenvironment.
Study TypeOther
Abstract Osteoclasts are multinucleated cells that are responsible for bone resorption. The differentiation of osteoclasts from bone marrow macrophages (BMM) is induced by receptor activator of NF-kB ligand (RANKL). Osteoprotegerin (OPG), a decoy receptor of RANKL, inhibits osteoclastogenesis by blocking RAN .. [more]
Description Osteoclasts are multinucleated cells that are responsible for bone resorption. The differentiation of osteoclasts from bone marrow macrophages (BMM) is induced by receptor activator of NF-kB ligand (RANKL). Osteoprotegerin (OPG), a decoy receptor of RANKL, inhibits osteoclastogenesis by blocking RAN .. [more]
Center NameSAITAMA_MED