| Title | RNA-seq of the lung adenocarcinoma cell line H1299 transfected with negative control or PLK1 siRNA. |
| Study Type | Other |
| Abstract |
PLK1 is an essential mitotic kinase in the mitotic progression and spindle bipolarity. It is known that PLK1 inhibition induces cell-cycle arrest and apoptosis in tumor cells. However, small things are known about apoptosis induced by PLK1 depletion. To know the gene that contributes to apoptosis in .. [more]duced by PLK1 inhibition, we comprehensively analyzed RNA expressions of the lung adenocarcinoma cell line H1299. We prepared two types of H1299 cells; PLK1 -depleted and -normal types. [less]
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| Description |
PLK1 is an essential mitotic kinase in the mitotic progression and spindle bipolarity. It is known that PLK1 inhibition induces cell-cycle arrest and apoptosis in tumor cells. However, small things are known about apoptosis induced by PLK1 depletion. To know the gene that contributes to apoptosis in .. [more]duced by PLK1 inhibition, we comprehensively analyzed RNA expressions of the lung adenocarcinoma cell line H1299. We prepared two types of H1299 cells; PLK1 -depleted and -normal types. [less]
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| Center Name | UT-MGS |
FTP
