Study Detail

TitleElucidation of biosynthetic genes for the meroterpenoid antibiotic ascofuranone using Acremonium sclerotigenum
Study TypeOther
Abstract Ascofuranone is a meroterpenoid with a strong inhibitory activity against cyanide-insensitive alternative oxidases and with demonstrated therapeutic efficacy in a rodent infection model of African trypanosomiasis. This project aims at elucidating the biosynthetic pathway and the underlying genes, by .. [more]
Description Ascofuranone is a meroterpenoid with a strong inhibitory activity against cyanide-insensitive alternative oxidases and with demonstrated therapeutic efficacy in a rodent infection model of African trypanosomiasis. This project aims at elucidating the biosynthetic pathway and the underlying genes, by .. [more]
Center NameNIID