Study Detail

TitleAkt Inhibition Synergizes with PRC2 inhibition in the Treatment of Multiple Myeloma
Study TypeOther
Abstract Polycomb repressive complex 2 (PRC2) components, EZH2 and its homolog EZH1, and PI3K/Akt signaling pathway are focal points as therapeutic targets for multiple myeloma (MM). However, the exact crosstalk between their downstream targets remains unclear. We herein elucidated epigenetic interactions fo .. [more]
Description Polycomb repressive complex 2 (PRC2) components, EZH2 and its homolog EZH1, and PI3K/Akt signaling pathway are focal points as therapeutic targets for multiple myeloma (MM). However, the exact crosstalk between their downstream targets remains unclear. We herein elucidated epigenetic interactions fo .. [more]
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