Study Detail

TitleHmga2 functions as an oncogene upon the deletion of Tet2 and promotes the pathogenesis of myelodysplastic syndrome.
Study TypeOther
Abstract High Mobility Group AT-hook 2 (HMGA2) has been found in a subset of patients with myeloid malignancies including myelodysplastic syndrome (MDS). Recent genome sequencing studies reveal the emergence of clonal hematopoiesis during aging as healthy aged people often harbor mutations of epigenetic modi .. [more]
Description High Mobility Group AT-hook 2 (HMGA2) has been found in a subset of patients with myeloid malignancies including myelodysplastic syndrome (MDS). Recent genome sequencing studies reveal the emergence of clonal hematopoiesis during aging as healthy aged people often harbor mutations of epigenetic modi .. [more]
Center NameIRCMS