Study Detail

TitleZebrafish Tilling by Illumina Sequencing
Study TypeWhole Genome Sequencing
Abstract Target selected mutagenesis, or TILLING (for targeting induced local lesions in genomes), is a proven method that allows mutations to be identified in virtually any gene. We have previously shown that capillary-sequencing can be used to effectively identify mutations in a high throughput manner. A l .. [more]
Description The Zebrafish is becoming a popular model organism for developmental biology and human disease. This increasing popularity has resulted in a demand for reverse genetics, which has traditionally been neglected in favour of forward genetic approaches because of the lack of an efficient gene knockout ( .. [more]
Center NameSC