Study Detail

TitleIdentification of genes responsible for S.mansoni resistance to oxamniquine
Study TypeWhole Genome Sequencing
Abstract Sequence a single genotype of S. mansoni. This will provide unambiguous sequence from a single isolate. Develop a SNP map for oxamniquine drug resistant and drug sensitive strains of S. manson.
Description A 5.6 cM genetic map of S. mansoni had been generated by the Anderson and LoVerde labs (Criscione et al., 2009). To identify drug resistant genes using the map, a male parent from the drug resistant strain was crossed with a female parent from a drug sensitive strain. The oxamniquine drug resistant .. [more]
Center NameSC