Study Detail

TitleDynamic CpG island methylation landscape in oocytes and preimplantation embryos
Study TypeEpigenetics
Abstract Elucidating how and to what extent CpG islands (CGIs) are methylated in germ cells is essential to understand genomic imprinting and epigenetic reprogramming1-3. Here, we present the first integrated epigenomic analysis of mammalian oocytes, identifying over a thousand CGIs methylated in mature oocy .. [more]
Center NameBI-UK