Study Detail

Study TypeWhole Genome Sequencing
Abstract The goal of this study is to identify the causal mutation associated with the developmental phenotypes found in the le mouse mutant. By generating pair-end sequence of the entire genome of this mouse we hope to identify rearranged genes for follow-up functional analysis.
Description We have identified a mouse with a radiation induced mutation that is associated with a range of developmental phenotypes. We have mapped the mutation to the X chromosome. To identify the gene that is disrupted we are sequencing the genome of this mouse.
Center NameSC