Study Detail

TitleThe clonal relationships between pre-cancer and cancer revealed by ultra-deep sequencing
Study TypePopulation Genomics
Abstract Previous work studying the clonal evolution of cancer has inferred the earliest mutations by comparisons of multiple patients or examination of variant allele frequencies. We performed ultra-deep sequencing of selected variants and copy number analysis from multiple pre-invasive lesions, primary tum .. [more]
Description Previous work studying the clonal evolution of cancer has inferred the earliest mutations by comparisons of multiple patients or examination of variant allele frequencies. We performed ultra-deep sequencing of selected variants and copy number analysis from multiple pre-invasive lesions, primary tum .. [more]
Center NameLeeds Institute of Molecular Medicine, University of Leeds, United Kingdom