Study Detail

TitleGenetic variability exceeds cell-type memory and determines iPSCs differentiation potential-implications for biobanking
Study TypeOther
Abstract To address the issue of retention of somatic cell memory in iPSCs we compared methylation profiles of genetically matched human iPSCs derived from fibroblasts and blood. We were using the all-in-one type footprint free SeVdp-iPS system, for generation of uniform iPSC lines. Our results show that iPS .. [more]
Description To address the issue of retention of somatic cell memory in iPSCs we compared methylation profiles of genetically matched human iPSCs derived from fibroblasts and blood. We were using the all-in-one type footprint free SeVdp-iPS system, for generation of uniform iPSC lines. Our results show that iPS .. [more]
Center NameUniversity of Washington