Study Detail

Study TypeTranscriptome Analysis
Abstract As mentioned before, the goal of this study consists of depicting the molecular mechanisms by which recently discovered tumor suppressor are able to constraint tumor development.
Description Transposon mutagenesis screens in mice has allowed us the identification of new tumor suppressor genes in cancer. To further explore the mechanistic role of these genes at the molecular level, we decided to study the transcriptome of human immortalized and cancer cells which underwent siRNA-mediated .. [more]
Center NameThe Wellcome Trust Sanger Institute