Study Detail

TitleComplete re-sequencing of a 2Mb topological domain encompassing FTO/IRXB genes identifies a novel obesity associated region upstream of IRX5
Study TypeOther
Abstract Background Association studies have identified a number of loci that contribute to an increased Body Mass Index (BMI), the strongest of which is in the first intron of the FTO gene on human chromosome 16q12.2. However, this region is both non-coding, and under strong linkage disequilibrium, making .. [more]
Description Background Association studies have identified a number of loci that contribute to an increased Body Mass Index (BMI), the strongest of which is in the first intron of the FTO gene on human chromosome 16q12.2. However, this region is both non-coding, and under strong linkage disequilibrium, making .. [more]
Center NameThe Francis Crick Institute