Study Detail

TitleExpression profiling of budding cells in colorectal cancer suggests an EMT-like phenotype and molecular subtype switching
Study TypeTranscriptome Analysis
Abstract Tumour buds undergo phenotype switching while detaching from the main tumour, as they acquire more migratory characteristics and tend to stop proliferating. Simultaneously, an EMT-like signature is observed in the tumour buds under the form of active WNT, TGF and receptor tyrosine kinase signalling. .. [more]
Description Tumour buds undergo phenotype switching while detaching from the main tumour, as they acquire more migratory characteristics and tend to stop proliferating. Simultaneously, an EMT-like signature is observed in the tumour buds under the form of active WNT, TGF and receptor tyrosine kinase signalling. .. [more]
Center NameLABORATORY OF TRANSLATIONAL GENETICS VESALIUS RESEARCH CENTER, VIB DEPARTMENT OF ONCOLOGY, KU LEUVEN