Title | miR-515 and migration in cancer |
Study Type | Other |
Abstract | We performed RNA-seq analyses of both estrogen receptor-positive and negative breast cancer cells over-expressing miR-515-5p which revealed down-regulation of several transcripts coding for migration promoting proteins. Modulating the expression of such proteins and miR-515 we found that miR-515 red .. [more]uced migration and metastatic behaviour through direct inhibition of such pro-metastatic genes. [less] |
Description | We performed RNA-seq analyses of both estrogen receptor-positive and negative breast cancer cells over-expressing miR-515-5p which revealed down-regulation of several transcripts coding for migration promoting proteins. Modulating the expression of such proteins and miR-515 we found that miR-515 red .. [more]uced migration and metastatic behaviour through direct inhibition of such pro-metastatic genes. [less] |
Center Name | Department of Surgery null, Imperial College London, UK |
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Submission | ERA538655 |
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Experiment | ERX1224746 |
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ERX1224747 |
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ERX1224748 |
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ERX1224749 |
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ERX1224750 |
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ERX1224751 |
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ERX1224752 |
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ERX1224753 |
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Sample | ERS983387 | ||
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ERS983389 | ||||
ERS983390 | ||||
ERS983391 | ||||
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ERS983393 | ||||
ERS983394 |