ERP013303

Title	miR-515 and migration in cancer
Study Type	Other
Abstract	We performed RNA-seq analyses of both estrogen receptor-positive and negative breast cancer cells over-expressing miR-515-5p which revealed down-regulation of several transcripts coding for migration promoting proteins. Modulating the expression of such proteins and miR-515 we found that miR-515 red .. [more]uced migration and metastatic behaviour through direct inhibition of such pro-metastatic genes. [less]
Description	We performed RNA-seq analyses of both estrogen receptor-positive and negative breast cancer cells over-expressing miR-515-5p which revealed down-regulation of several transcripts coding for migration promoting proteins. Modulating the expression of such proteins and miR-515 we found that miR-515 red .. [more]uced migration and metastatic behaviour through direct inhibition of such pro-metastatic genes. [less]
Center Name	Department of Surgery null, Imperial College London, UK

DRASearch