Study Detail

TitleHigh prevalence of TP53 mutations is associated with poor survival and epithelial-mesenchymal transition signature in gliosarcoma patients
Study TypeOther
Abstract Gliosarcoma (GS) is a rare variant (2%) of glioblastoma (GBM) and poses clinical genomic challenges because of poor prognosis and limited genomic information1-3. To understand the molecular etiology of GS, we applied whole-exome sequencing for 28 GS cases from different patient cohorts. Mutations of .. [more]
Description Gliosarcoma (GS) is a rare variant (2%) of glioblastoma (GBM) and poses clinical genomic challenges because of poor prognosis and limited genomic information1-3. To understand the molecular etiology of GS, we applied whole-exome sequencing for 28 GS cases from different patient cohorts. Mutations of .. [more]
Center NameSeoul National University, Korea