Study Detail

TitleOpioid-induced gut microbial disruption leads to gut barrier compromise and sustained systemic inflammation.
Study TypeOther
Abstract Morphine and its pharmacological derivatives are the most prescribed analgesics for moderate to severe pain management. However, chronic use of morphine reduces pathogen clearance and induces bacterial translocation across the gut barrier. The enteric microbiome has been shown to play a critical rol .. [more]
Description Morphine and its pharmacological derivatives are the most prescribed analgesics for moderate to severe pain management. However, chronic use of morphine reduces pathogen clearance and induces bacterial translocation across the gut barrier. The enteric microbiome has been shown to play a critical rol .. [more]
Center NameDepartment of Surgery, BTR University of Minnesota