Study Detail

TitleEffect of hypoxia and atpenin A5 on the human monocyte transcriptome
Study TypeOther
Abstract Monocyte-enriched peripheral blood mononuclear cells of apparently healthy human blood donors were cultured under normoxia or hypoxia (1% O2) for 24 hours at a high density (>20 million/ml). Normoxic cultures were also treated with 1 uM atpenin A5 for 48 hours. Afterwards, CD14+ monocytes were isola .. [more]
Description Monocyte-enriched peripheral blood mononuclear cells of apparently healthy human blood donors were cultured under normoxia or hypoxia (1% O2) for 24 hours at a high density (>20 million/ml). Normoxic cultures were also treated with 1 uM atpenin A5 for 48 hours. Afterwards, CD14+ monocytes were isola .. [more]
Center NameROSWELL PARK CANCER INSTITUTE