Study Detail

TitleCell plasticity identifies an epigenetically distinct cancer subpopulation driving drug resistance and progression
Study TypeOther
Abstract The Cancer Stem Cells (CSCs) hypothesis implies the existence of progenitor breast cancer cells with de-novo resistance toward anti oestrogen-receptor therapies. Here we demonstrate that putative CSCs are epigenetically distinct from the main tumour population. CSCs are resilient but not compl .. [more]
Description The Cancer Stem Cells (CSCs) hypothesis implies the existence of progenitor breast cancer cells with de-novo resistance toward anti oestrogen-receptor therapies. Here we demonstrate that putative CSCs are epigenetically distinct from the main tumour population. CSCs are resilient but not compl .. [more]
Center NameIMPERIAL CENTRE FOR TRANSLATIONAL AND EXPERIMENTAL MEDICINE