Study Detail

TitlePolymerase Specific Error Rates and Profiles Identified by PacBio Single Molecule Sequencing
Study TypeOther
Abstract DNA polymerases have an innate error rate which is polymerase and DNA context specific. We used the unique properties of PacBio single molecule sequencing to directly evaluate the mutational rate and profiles of amplicons generated by six commonly used DNA polymerases. Primers targeted the CASK and .. [more]
Description DNA polymerases have an innate error rate which is polymerase and DNA context specific. We used the unique properties of PacBio single molecule sequencing to directly evaluate the mutational rate and profiles of amplicons generated by six commonly used DNA polymerases. Primers targeted the CASK and .. [more]
Center NameKU LEUVEN