Study Detail

Study TypeTranscriptome Analysis
Abstract This study is based on the importance of stem cells in future medicine and the need to understand the fundamental mechanisms that regulate their potential to differentiate towards specific lineages. We aim to gather the information required to understand the regulatory networks of key stem cells and .. [more]
Description We aim to characterize transcriptional changes in mouse embryonic stem (ES) cells and mouse epiblast stem (EpiS) cells following the knockdown of essential genes identified in genome-wide RNAi screens. ES or EpiS cells were treated with esiRNA for 125 candidate genes and total RNA was collected fro .. [more]
Center NameThe Wellcome Trust Sanger Institute