Study Detail

TitleFunctional sequestration of MOAG-2/LIR-3 by polyglutamine expansion proteins
Study TypeTranscriptome Analysis
Abstract Transcriptome profiling of Lir3 C.elegans mutants. Larval stage L4 worms were used for RNA isolation from N2 (Bristol), Q40 (polyglutamine model) genetic background; Lir3 and wiltype controls. Experiments were done in triplicates using ribosomal RNA depletion. Libraries were sequenced with 50bp read .. [more]
Description Transcriptome profiling of Lir3 C.elegans mutants. Larval stage L4 worms were used for RNA isolation from N2 (Bristol), Q40 (polyglutamine model) genetic background; Lir3 and wiltype controls. Experiments were done in triplicates using ribosomal RNA depletion. Libraries were sequenced with 50bp read .. [more]
Center NameEuropean Research Institute for the Biology of Ageing (ERIBA), University of Groningen, UMC Groningen