Study Detail

TitleIdentification of target genes of the transcription factors TCF1 and TCF3 in mouse embryonic stem cells (ChIP-Seq)
Study TypeWhole Genome Sequencing
Abstract Wnt/-catenin signaling controls self-renewal and pluripotency maintenance in both embryonic and adult stem cells (SCs) in mouse. We show that the activation of Wnt pathway drastically reduces proliferation of mESCs by direct binding of the the Wnt-effector Tcf1 to directly binds and regulates the In .. [more]
Description Wnt/-catenin signaling controls self-renewal and pluripotency maintenance in both embryonic and adult stem cells (SCs) in mouse. We show that the activation of Wnt pathway drastically reduces proliferation of mESCs by direct binding of the the Wnt-effector Tcf1 to directly binds and regulates the In .. [more]
Center NameResearch Associate