Study Detail

Study TypeTranscriptome Analysis
Abstract Tumour infiltrating leukocytes (TIL) are crucial in anti-tumour immunity. In established tumour the tumour microenvironment is often immunosuppressive. Studying single-cell transcriptome of TILs we are intended to discover new immunosuppressive gene regulatory network.
Description Murine tumour infiltrating lymphocytes (CD8+ T cells) were index-sorted based on expression of CD8a and CD3e. Subsequently cDNA was generated from these samples using the Smart-seq2 protocol. This data is part of a pre-publication release. For information on the proper use of pre-publica .. [more]
Center NameThe Wellcome Trust Sanger Institute