Study Detail

TitleOesophageal adenocarcinoma exome sequence data from samples before and after neo-adjuvant chemotherapy
Study TypeOther
Abstract How chemotherapy affects carcinoma genomes is largely unknown. Here, we performed whole-exome and deep sequencing of 30 paired oesophageal adenocarcinomas sampled before and after neo-adjuvant chemotherapy. Most, but not all, good responders passed through genetic bottlenecks. Some poor responde .. [more]
Description How chemotherapy affects carcinoma genomes is largely unknown. Here, we performed whole-exome and deep sequencing of 30 paired oesophageal adenocarcinomas sampled before and after neo-adjuvant chemotherapy. Most, but not all, good responders passed through genetic bottlenecks. Some poor responde .. [more]
Center NameWellcome Trust Centre for Human Genetics