Study Detail

TitleIn Vivo Functional Platform Targeting Patient- Derived Xenografts Identifies WDR5-Myc Association as a Critical Determinant of Pancreatic Cancer
Study TypeOther
Abstract Current treatment regimens for pancreatic ductal adenocarcinoma (PDAC) yield poor 5-year survival, emphasizing the critical need to identify new druggable targets essential for PDAC maintenance. We developed an unbiased, in vivo target discovery approach to interrogate tumor-initiating cell (TIC) vu .. [more]
Description Current treatment regimens for pancreatic ductal adenocarcinoma (PDAC) yield poor 5-year survival, emphasizing the critical need to identify new druggable targets essential for PDAC maintenance. We developed an unbiased, in vivo target discovery approach to interrogate tumor-initiating cell (TIC) vu .. [more]
Center NameMD ANDERSON CANCER CENTER