Study Detail

TitleMutations in ppe38 block PE_PGRS secretion and cause hypervirulence in Mycobacterium tuberculosis
Study TypeOther
Abstract Mycobacterium tuberculosis requires a large number of secreted and exported proteins for its virulence, immune modulation and nutrient uptake. Most of these proteins are transported via the different typeVII secretion (T7S) systems that are present in this pathogen. The most recently evolved T7S sys .. [more]
Description Mycobacterium tuberculosis requires a large number of secreted and exported proteins for its virulence, immune modulation and nutrient uptake. Most of these proteins are transported via the different typeVII secretion (T7S) systems that are present in this pathogen. The most recently evolved T7S sys .. [more]
Center NameSAMRC Centre for Tuberculosis Research