Study Detail

TitleGerm line variants in cancer-related genes of early-onset South African breast cancer patients
Study TypeOther
Abstract We evaluated germline variation in DNA damage response associated genes in individuals from hereditary breast cancer families with and without BRCA1/2 truncating variants. Whole exome variant data from eight BRCA negative and four BRCA1/2 mutation-positive individuals was used to investigate mutatio .. [more]
Description We evaluated germline variation in DNA damage response associated genes in individuals from hereditary breast cancer families with and without BRCA1/2 truncating variants. Whole exome variant data from eight BRCA negative and four BRCA1/2 mutation-positive individuals was used to investigate mutatio .. [more]
Center NameUNIVERSITY OF PRETORIA