Study Detail

TitleGenome-wide DNA methylation landscape defines specialization of regulatory T cells in tissues
Study TypeOther
Abstract Regulatory T cells (Treg) perform two distinct functions: they maintain self-tolerance and support organ homeostasis by differentiation into specialized tissue Treg cells. We now report that epigenetic adaptations define molecular characteristics of tissue Treg cells. Whole-genome bisulfite sequenci .. [more]
Description Regulatory T cells (Treg) perform two distinct functions: they maintain self-tolerance and support organ homeostasis by differentiation into specialized tissue Treg cells. We now report that epigenetic adaptations define molecular characteristics of tissue Treg cells. Whole-genome bisulfite sequenci .. [more]
Center NameGerman Cancer Research Center (DKFZ), Heidelberg, Germany