Study Detail

TitleImpact of aging on cell-to-cell transcriptional variability during immune stimulation
Study TypeTranscriptome Analysis
Abstract We explored how aging impacts transcriptional dynamics using single-cell RNA-sequencing to profile hundreds of CD4+ T cells from young and old mice from two divergent species. In young animals, immunological challenge drives a conserved transcriptomic switch from highly variable to tightly regulated .. [more]
Description We explored how aging impacts transcriptional dynamics using single-cell RNA-sequencing to profile hundreds of CD4+ T cells from young and old mice from two divergent species. In young animals, immunological challenge drives a conserved transcriptomic switch from highly variable to tightly regulated .. [more]
Center NameEMBL-EBI