ERP016433

Title	RNA-seq of sh2-H2AFJ and sh-NoTarget in WI-38hTERT cells induced into senescence by etoposide
Study Type	Transcriptome Analysis
Abstract	Study the role of H2A.J in gene expression in senescent human fibroblasts by comparing RNA-seq of WI-38hTERT fibroblasts expressing either an sh2-H2AFJ or sh-NoTarget RNAs. Senescence was induced by treating cells with 20 µM etoposide for 2 weeks followed by one further week of incubation without et .. [more]oposide. 3 biological replicates of sh2-H2AFJ and sh-NoTarget were sequenced. [less]
Description	Study the role of H2A.J in gene expression in senescent human fibroblasts by comparing RNA-seq of WI-38hTERT fibroblasts expressing either an sh2-H2AFJ or sh-NoTarget RNAs. Senescence was induced by treating cells with 20 µM etoposide for 2 weeks followed by one further week of incubation without et .. [more]oposide. 3 biological replicates of sh2-H2AFJ and sh-NoTarget were sequenced. [less]
Center Name	Service de Biologie Integrative et Genetique Moleculaire (SBIGeM)/I2BC/UMR9198-CEA/CNRS/Universite Paris-Saclay

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