Study Detail

TitleThe evolutionary conserved transcription factor Sp1 controls appendage growth through Notch signaling
Study TypeOther
Abstract The appendages of arthropods and vertebrates are not homologous structures; however the underlying genetic mechanisms that pattern them are highly conserved. Members of the Sp family of transcription factors are expressed in the developing limbs and their function is required for limb growth in both .. [more]
Description The appendages of arthropods and vertebrates are not homologous structures; however the underlying genetic mechanisms that pattern them are highly conserved. Members of the Sp family of transcription factors are expressed in the developing limbs and their function is required for limb growth in both .. [more]
Center NameCentro Biologia Molecular Severo Ochoa (CBMSO)