Study Detail

TitleTCR repertoire sequencing of mucosal Foxp3+RORgt+ regulatory T cells
Study TypeOther
Abstract Foxp3+RORgt+ T cells have recently been characterized as an immunoregulatory population highly enriched in the colon lamina propria. However, their relation to RORgt- Treg and TH17 cells remains unclear. Here, we use a fixed TCRb system to show that the TCR repertoire of the Foxp3+RORgt+ population .. [more]
Description Foxp3+RORgt+ T cells have recently been characterized as an immunoregulatory population highly enriched in the colon lamina propria. However, their relation to RORgt- Treg and TH17 cells remains unclear. Here, we use a fixed TCRb system to show that the TCR repertoire of the Foxp3+RORgt+ population .. [more]
Center NameWASHINGTON UNIVERSITY SCHOOL OF MEDICINE