Study Detail

TitleThis study provides detailed structure-function information of single-domain antibodies binding influenza hemagglutinin, information which further supports the suitability of nanobodies as universal binding reagents for vaccine potency assays.
Study TypeOther
Abstract Understanding the precise structure and function of cross-neutralising single domain antibodies (nanobodies) against influenza is crucial in evaluating their potential as analytical reagents and immunotherapeutics. By using yeast display in combination with deep mutational scanning, we have generate .. [more]
Description Understanding the precise structure and function of cross-neutralising single domain antibodies (nanobodies) against influenza is crucial in evaluating their potential as analytical reagents and immunotherapeutics. By using yeast display in combination with deep mutational scanning, we have generate .. [more]
Center NameNIBSC