Study Detail

TitleOur hypothesis is that the host genetics controls to some extent the composition of the skin microbiota. To test this hypothesis, we first generated a fifteen generation from an advanced mouse intercross line, defined the relative abundances of skin resident bacterial taxa, both using the 16S rRNA gene copy (DNA)- and transcript (RNA) level, and performed QTL mapping on the active (RNA)- and standing (DNA) communities.
Study TypeOther
Abstract Recent studies highlight the utility of quantitative trait locus (QTL) mapping for determining the contribution of host genetics to inter-individual variation in the microbiota. We previously demonstrated that similar to the gut microbiota, abundances of bacterial taxa in the skin are significantly .. [more]
Description Recent studies highlight the utility of quantitative trait locus (QTL) mapping for determining the contribution of host genetics to inter-individual variation in the microbiota. We previously demonstrated that similar to the gut microbiota, abundances of bacterial taxa in the skin are significantly .. [more]
Center NameMAX PLANCK INSTITUTE FOR EVOLUTIONARY BIOLOGY