Study Detail

TitleMultifaceted dysfunction of infant airway macrophages in response to Mycobacterium tuberculosis
Study TypeTranscriptome Analysis
Abstract Infants are vulnerable to disseminated forms of tuberculosis and suffer disproportionately high morbidity and mortality, but the reasons for this are unknown. We hypothesized that since alveolar macrophages (AMs) are critical in the uptake and containment of Mycobacterium tuberculosis (Mtb) in the l .. [more]
Description Infants are vulnerable to disseminated forms of tuberculosis and suffer disproportionately high morbidity and mortality, but the reasons for this are unknown. We hypothesized that since alveolar macrophages (AMs) are critical in the uptake and containment of Mycobacterium tuberculosis (Mtb) in the l .. [more]
Center NameUNIVERSITY OF MANCHESTER