Study Detail

TitleDetection of Base Analogs Incorporated During DNA Replication by Nanopore Sequencing
Study TypeOther
Abstract DNA synthesis is a fundamental requirement for cell proliferation and DNA repair, but no tools exist to identify the location, direction and speed of replication forks with base pair resolution. Mammalian cells have the ability to incorporate thymidine analogs along with the natural A, T, G and C ba .. [more]
Description DNA synthesis is a fundamental requirement for cell proliferation and DNA repair, but no tools exist to identify the location, direction and speed of replication forks with base pair resolution. Mammalian cells have the ability to incorporate thymidine analogs along with the natural A, T, G and C ba .. [more]
Center NameColumbia University